Hint: noatime and relatime in fstab
Stop pointless atime writes on database volumes.
Atime updates turn reads into metadata writes. Database data directories rarely need atime.
Options
/dev/mapper/vg-data /var/lib/mysql ext4 defaults,noatime 0 2
noatime disables atime updates.
Modern kernels default to relatime (update atime only when older than mtime/ctime or past a threshold). Document intent:
defaults,relatime,nodiratime
Verify
findmnt /var/lib/mysql
grep mysql /proc/mounts
NFS
Attribute traffic on NFS is a separate cost. Prefer local/block volumes for InnoDB tablespaces. Measure before putting data files on NFS.
Small mount change. Removes a class of self-inflicted latency before you touch InnoDB tunables.